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Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.\" [GOC:go_curators]","accession":"GO:0043234","synonyms":["protein-protein complex"]},"is_a":[{"namespace":"cellular_component","definition":"\"A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.\" [GOC:mah]","subsets":["goslim_pir","gosubset_prok"],"ontology":"GO","name":"macromolecular complex","synonyms":["macromolecule complex"],"accession":"GO:0032991"}]},"GO:0032991":{"is_a":[{"ontology":"GO","subsets":["goslim_aspergillus","goslim_candida","goslim_generic","goslim_metagenomics","goslim_pir","goslim_plant","goslim_yeast","gosubset_prok"],"namespace":"cellular_component","definition":"\"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.\" [GOC:go_curators]","name":"cellular_component","synonyms":["cellular component","cellular component unknown"],"accession":"GO:0005575"}],"term":{"accession":"GO:0032991","synonyms":["macromolecule complex"],"name":"macromolecular complex","ontology":"GO","subsets":["goslim_pir","gosubset_prok"],"definition":"\"A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.\" [GOC:mah]","namespace":"cellular_component"}},"GO:0044424":{"part_of":[{"namespace":"cellular_component","definition":"\"The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.\" [ISBN:0198506732]","ontology":"GO","subsets":["goslim_generic","goslim_pir","goslim_plant","gosubset_prok"],"name":"intracellular","synonyms":["internal to cell","nucleocytoplasm","protoplasm","protoplast"],"accession":"GO:0005622"}],"term":{"name":"intracellular part","definition":"\"Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.\" [GOC:jl]","namespace":"cellular_component","subsets":["gocheck_do_not_annotate","gosubset_prok"],"ontology":"GO","accession":"GO:0044424","synonyms":[]},"is_a":[{"namespace":"cellular_component","definition":"\"Any constituent part of a cell, the basic structural and functional unit of all organisms.\" [GOC:jl]","ontology":"GO","subsets":["gocheck_do_not_annotate","goslim_pir","gosubset_prok"],"name":"cell part","synonyms":["protoplast"],"accession":"GO:0044464"}]},"GO:0044464":{"part_of":[{"accession":"GO:0005623","synonyms":[],"name":"cell","namespace":"cellular_component","definition":"\"The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.\" [GOC:go_curators]","ontology":"GO","subsets":["goslim_generic","goslim_plant","gosubset_prok"]}],"term":{"name":"cell part","definition":"\"Any constituent part of a cell, the basic structural and functional unit of all organisms.\" [GOC:jl]","namespace":"cellular_component","ontology":"GO","subsets":["gocheck_do_not_annotate","goslim_pir","gosubset_prok"],"accession":"GO:0044464","synonyms":["protoplast"]},"is_a":[{"synonyms":["cellular component","cellular component unknown"],"accession":"GO:0005575","subsets":["goslim_aspergillus","goslim_candida","goslim_generic","goslim_metagenomics","goslim_pir","goslim_plant","goslim_yeast","gosubset_prok"],"ontology":"GO","namespace":"cellular_component","definition":"\"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.\" [GOC:go_curators]","name":"cellular_component"}]},"GO:0005575":{"term":{"synonyms":["cellular component","cellular component unknown"],"accession":"GO:0005575","namespace":"cellular_component","definition":"\"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.\" [GOC:go_curators]","ontology":"GO","subsets":["goslim_aspergillus","goslim_candida","goslim_generic","goslim_metagenomics","goslim_pir","goslim_plant","goslim_yeast","gosubset_prok"],"name":"cellular_component"}},"GO:0005623":{"is_a":[{"subsets":["goslim_aspergillus","goslim_candida","goslim_generic","goslim_metagenomics","goslim_pir","goslim_plant","goslim_yeast","gosubset_prok"],"ontology":"GO","namespace":"cellular_component","definition":"\"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.\" [GOC:go_curators]","name":"cellular_component","synonyms":["cellular component","cellular component unknown"],"accession":"GO:0005575"}],"term":{"name":"cell","subsets":["goslim_generic","goslim_plant","gosubset_prok"],"ontology":"GO","definition":"\"The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.\" [GOC:go_curators]","namespace":"cellular_component","accession":"GO:0005623","synonyms":[]}},"GO:0005622":{"term":{"synonyms":["internal to cell","nucleocytoplasm","protoplasm","protoplast"],"accession":"GO:0005622","subsets":["goslim_generic","goslim_pir","goslim_plant","gosubset_prok"],"ontology":"GO","definition":"\"The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.\" [ISBN:0198506732]","namespace":"cellular_component","name":"intracellular"},"is_a":[{"subsets":["gocheck_do_not_annotate","goslim_pir","gosubset_prok"],"ontology":"GO","namespace":"cellular_component","definition":"\"Any constituent part of a cell, the basic structural and functional unit of all organisms.\" [GOC:jl]","name":"cell part","synonyms":["protoplast"],"accession":"GO:0044464"}]},"GO:0005667":{"term":{"accession":"GO:0005667","synonyms":[],"name":"transcription factor complex","namespace":"cellular_component","definition":"\"A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.\" [GOC:jl]","ontology":"GO","subsets":["goslim_metagenomics","goslim_pir"]},"is_a":[{"definition":"\"Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.\" [GOC:go_curators]","namespace":"cellular_component","subsets":["goslim_generic","goslim_pir","gosubset_prok"],"ontology":"GO","name":"protein complex","synonyms":["protein-protein complex"],"accession":"GO:0043234"},{"accession":"GO:0044424","synonyms":[],"name":"intracellular part","definition":"\"Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.\" [GOC:jl]","namespace":"cellular_component","subsets":["gocheck_do_not_annotate","gosubset_prok"],"ontology":"GO"}]}}